WNK1 (NM_213655) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]
Synonyms
HSAN2; HSN2; KDP; p65; PPP1R167; PRKWNK1; PSK
Gene ID
65125
UniProt
Q9H4A3
Accession Number mRNA
NM_213655
Chromosomal Location
12p13.33
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Protein Kinase
Molecular Weight
29.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
WNK1
Species
Human
Protein ID
NP_998820
Overview
Purified recombinant protein of Human WNK lysine deficient protein kinase 1 (WNK1), transcript variant 3, Thr104-Ala373, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/65125
Uniprot URL
https://www.uniprot.org/uniprot/Q9H4A3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_213655
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_998820
Curated Selection
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