HIF3 alpha (HIF3A) (NM_152795) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia) . The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
Overview
Purified recombinant protein of Human hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 3, Gln355-End, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
BHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7
Gene ID
64344
UniProt
Q9Y2N7
Accession Number mRNA
NM_152795
Chromosomal Location
19q13.32
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Transcription Factors
Molecular Weight
33.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HIF3A
Species
Human
Protein ID
NP_690008
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/64344
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y2N7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_152795
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_690008
Frequently Asked Questions
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