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HIF3 alpha (HIF3A) (NM_152795) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia) . The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

Overview

Purified recombinant protein of Human hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 3, Gln355-End, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

BHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7

Gene ID

64344

UniProt

Q9Y2N7

Accession Number mRNA

NM_152795

Chromosomal Location

19q13.32

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Function

Druggable Genome, Transcription Factors

Molecular Weight

33.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HIF3A

Species

Human

Protein ID

NP_690008

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/64344

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y2N7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_152795

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_690008

Frequently Asked Questions

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