TET2 (NM_001127208) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Overview

Purified recombinant protein of Human tet oncogene family member 2 (TET2), transcript variant 1, Lys423-Gln740, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

IMD75; KIAA1546; MDS

Gene ID

54790

UniProt

Q6N021, A0A158SIU0

Accession Number mRNA

NM_001127208

Chromosomal Location

4q24

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Molecular Weight

36.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.