TET2 (NM_001127208) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Synonyms
IMD75; KIAA1546; MDS
Gene ID
54790
UniProt
Q6N021, A0A158SIU0
Accession Number mRNA
NM_001127208
Chromosomal Location
4q24
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Weight
36.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TET2
Species
Human
Protein ID
NP_001120680
Overview
Purified recombinant protein of Human tet oncogene family member 2 (TET2), transcript variant 1, Lys423-Gln740, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54790
Uniprot URL
https://www.uniprot.org/uniprot/Q6N021
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001127208
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001120680
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