Kv2.1 (KCNB1) (NM_004975) Human Recombinant Protein
Product Specifications
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
Synonyms
DEE26; DRK1; Kv2.1
Gene ID
3745
UniProt
Q14721
Accession Number mRNA
NM_004975
Chromosomal Location
20q13.13
Expression System
E. coli
Tag
N-His
Related Pathways
Taste transduction
Field of Research
Taste transduction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Function
Druggable Genome, Ion Channels: Potassium, Transmembrane
Molecular Weight
32.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KCNB1
Species
Human
Protein ID
NP_004966
Overview
Purified recombinant protein of Human potassium voltage-gated channel, Shab-related subfamily, member 1 (KCNB1), Gln509-Cys813, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3745
Uniprot URL
https://www.uniprot.org/uniprot/Q14721
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004975
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004966
Curated Selection
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