KEL (NM_000420) Human Recombinant Protein
Selected Variant
PH30370E1
Size: 50 µg
Product Specifications
Background
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human Kell blood group, metallo-endopeptidase (KEL), Thr166-Pro420, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
CD238; ECE3; Kell
Gene ID
3792
UniProt
P23276, A0A077QP03
Accession Number mRNA
NM_000420
Chromosomal Location
7q34
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Protease, Transmembrane
Molecular Weight
29.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KEL
Species
Human
Protein ID
NP_000411
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3792
Uniprot URL
https://www.uniprot.org/uniprot/P23276
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000420
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000411
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