Macrophage Inflammatory Protein 3 alpha (CCL20) (NM_004591) Human Recombinant Protein
Product Specifications
Background
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Synonyms
CKb4; Exodus; LARC; MIP-3-alpha; MIP-3a; MIP3A; SCYA20; ST38
Gene ID
6364
UniProt
P78556
Accession Number mRNA
NM_004591
Chromosomal Location
2q36.3
Expression System
E. coli
Tag
N-His-PDCD1 (Pro21-Val170)
Related Pathways
Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Field of Research
Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Secreted Protein
Molecular Weight
24.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CCL20
Species
Human
Protein ID
NP_004582
Overview
Purified recombinant protein of Human chemokine (C-C motif) ligand 20 (CCL20), transcript variant 1, Ser27-End, with N-terminal His-PDCD1 (Pro21-Val170) tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6364
Uniprot URL
https://www.uniprot.org/uniprot/P78556
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004591
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004582
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