Macrophage Inflammatory Protein 3 alpha (CCL20) (NM_004591) Human Recombinant Protein

Product Specifications

Background

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Overview

Purified recombinant protein of Human chemokine (C-C motif) ligand 20 (CCL20), transcript variant 1, Ser27-End, with N-terminal His-PDCD1 (Pro21-Val170) tag, expressed in E. coli, 50ug

Synonyms

CKb4; Exodus; LARC; MIP-3-alpha; MIP-3a; MIP3A; SCYA20; ST38

Gene ID

6364

UniProt

P78556

Accession Number mRNA

NM_004591

Chromosomal Location

2q36.3

Expression System

E. coli

Tag

N-His-PDCD1 (Pro21-Val170)

Related Pathways

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Field of Research

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0.

Function

Druggable Genome, Secreted Protein

Molecular Weight

24.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.