BNIP3L (NM_004331) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]
Overview
Purified recombinant protein of Human BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L), Met1-Lys187, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
BNIP3a; NIX
Gene ID
665
UniProt
O60238, Q6IBV1
Accession Number mRNA
NM_004331
Chromosomal Location
8p21.2
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Transmembrane
Molecular Weight
20.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BNIP3L
Species
Human
Protein ID
NP_004322
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/665
Uniprot URL
https://www.uniprot.org/uniprot/O60238
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004331
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004322
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