FASTK (NM_006712) Human Recombinant Protein
Selected Variant
PH30346E1
Size: 50 µg
Product Specifications
Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
Overview
Purified recombinant protein of Human Fas-activated serine/threonine kinase (FASTK), transcript variant 1, Leu200-Gln535, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
FAST
Gene ID
10922
UniProt
Q14296, A0A090N8Z7
Accession Number mRNA
NM_006712
Chromosomal Location
7q36.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Protein Kinase
Molecular Weight
38.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FASTK
Species
Human
Protein ID
NP_006703
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10922
Uniprot URL
https://www.uniprot.org/uniprot/Q14296
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006712
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006703
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