PLAAT4 (NM_004585) Human Recombinant Protein
Product Specifications
Background
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008]
Synonyms
HRASLS4; HRSL4; PLA1/2-3; PLAAT-4; RARRES3; RIG1; TIG3
Gene ID
5920
UniProt
Q9UL19
Accession Number mRNA
NM_004585
Chromosomal Location
11q12.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0.
Function
Druggable Genome, Nuclear Hormone Receptor, Transmembrane
Molecular Weight
18 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLAAT4
Species
Human
Protein ID
NP_004576
Overview
Purified recombinant protein of Human retinoic acid receptor responder (tazarotene induced) 3 (RARRES3), full length, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5920
Uniprot URL
https://www.uniprot.org/uniprot/Q9UL19
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004585
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004576
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