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MGAT1 (NM_002406) Human Recombinant Protein

Product Specifications

Background

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human mannosyl (alpha-1, 3-) -glycoprotein beta-1, 2-N-acetylglucosaminyltransferase (MGAT1), transcript variant 2, Trp241-end, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; GnTI; MGAT

Gene ID

4245

UniProt

P26572

Accession Number mRNA

NM_002406

Chromosomal Location

5q35.3

Expression System

E. coli

Tag

N-His

Related Pathways

Metabolic pathways, N-Glycan biosynthesis

Field of Research

Metabolic pathways, N-Glycan biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0

Function

Druggable Genome, Transmembrane

Molecular Weight

24.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MGAT1

Species

Human

Protein ID

NP_002397

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4245

Uniprot URL

https://www.uniprot.org/uniprot/P26572

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002406

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002397

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