MGAT1 (NM_002406) Human Recombinant Protein
Product Specifications
Background
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; GnTI; MGAT
Gene ID
4245
UniProt
P26572
Accession Number mRNA
NM_002406
Chromosomal Location
5q35.3
Expression System
E. coli
Tag
N-His
Related Pathways
Metabolic pathways, N-Glycan biosynthesis
Field of Research
Metabolic pathways, N-Glycan biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0
Function
Druggable Genome, Transmembrane
Molecular Weight
24.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MGAT1
Species
Human
Protein ID
NP_002397
Overview
Purified recombinant protein of Human mannosyl (alpha-1, 3-) -glycoprotein beta-1, 2-N-acetylglucosaminyltransferase (MGAT1), transcript variant 2, Trp241-end, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4245
Uniprot URL
https://www.uniprot.org/uniprot/P26572
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002406
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002397
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