Snf1lk (SIK1) (NM_173354) Human Recombinant Protein
Product Specifications
Background
This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily of kinases that play a role in conserved signal transduction pathways. A mutation in this gene is associated with early infantile epileptic encephalopathy 30. [provided by RefSeq, Nov 2016]
Overview
Purified recombinant protein of Human salt-inducible kinase 1 (SIK1), Tyr27-Met278, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
DEE30; MSK; SIK; SIK-1; SIK1B; SNF1LK
Gene ID
150094
UniProt
P57059
Accession Number mRNA
NM_173354
Chromosomal Location
21q22.3
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0
Function
Druggable Genome, Protein Kinase
Molecular Weight
29.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SIK1
Species
Human
Protein ID
NP_775490
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/150094
Uniprot URL
https://www.uniprot.org/uniprot/P57059
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173354
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_775490
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