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Snf1lk (SIK1) (NM_173354) Human Recombinant Protein

Product Specifications

Background

This gene encodes a serine/threonine protein kinase that contains a ubiquitin-associated (UBA) domain. The encoded protein is a member of the adenosine monophosphate-activated kinase (AMPK) subfamily of kinases that play a role in conserved signal transduction pathways. A mutation in this gene is associated with early infantile epileptic encephalopathy 30. [provided by RefSeq, Nov 2016]

Overview

Purified recombinant protein of Human salt-inducible kinase 1 (SIK1), Tyr27-Met278, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

DEE30; MSK; SIK; SIK-1; SIK1B; SNF1LK

Gene ID

150094

UniProt

P57059

Accession Number mRNA

NM_173354

Chromosomal Location

21q22.3

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0

Function

Druggable Genome, Protein Kinase

Molecular Weight

29.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SIK1

Species

Human

Protein ID

NP_775490

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/150094

Uniprot URL

https://www.uniprot.org/uniprot/P57059

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_173354

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_775490

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