SLC26A3 (NM_000111) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008]
Overview
Purified recombinant protein of Human solute carrier family 26, member 3 (SLC26A3), Phe505-end, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
CLD; DRA
Gene ID
1811
UniProt
P40879
Accession Number mRNA
NM_000111
Chromosomal Location
7q22.3-q31.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0
Function
Druggable Genome, Transcription Factors, Transmembrane
Molecular Weight
30.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SLC26A3
Species
Human
Protein ID
NP_000102
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1811
Uniprot URL
https://www.uniprot.org/uniprot/P40879
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000111
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000102
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