TRIB3 (NM_021158) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
Synonyms
C20orf97; NIPK; SINK; SKIP3; TRB3
Gene ID
57761
UniProt
Q96RU7
Accession Number mRNA
NM_021158
Chromosomal Location
20p13
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0
Function
Druggable Genome, Protein Kinase, Transcription Factors
Molecular Weight
22.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TRIB3
Species
Human
Protein ID
NP_066981
Overview
Purified recombinant protein of Human tribbles homolog 3 (Drosophila) (TRIB3), Met1-Leu200, with N-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57761
Uniprot URL
https://www.uniprot.org/uniprot/Q96RU7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021158
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_066981
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