TRIB3 (NM_021158) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]

Overview

Purified recombinant protein of Human tribbles homolog 3 (Drosophila) (TRIB3), Met1-Leu200, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

C20orf97; NIPK; SINK; SKIP3; TRB3

Gene ID

57761

UniProt

Q96RU7

Accession Number mRNA

NM_021158

Chromosomal Location

20p13

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0

Function

Druggable Genome, Protein Kinase, Transcription Factors

Molecular Weight

22.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.