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VRK2 (NM_006296) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]

Overview

Purified recombinant protein of Human vaccinia related kinase 2 (VRK2), transcript variant 1, Asp301-Asp486, with N-terminal His tag, expressed in E. coli, 50ug

Synonyms

Vaccinia-related kinase-2; vaccinia related kinase 2; vaccinia virus B1R-related kinase 2

Gene ID

7444

UniProt

Q86Y07

Accession Number mRNA

NM_006296

Chromosomal Location

2p16.1

Expression System

E. coli

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris, 8M Urea, pH8.0

Function

Druggable Genome, Protein Kinase, Transmembrane

Molecular Weight

21.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

VRK2

Species

Human

Protein ID

NP_006287

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7444

Uniprot URL

https://www.uniprot.org/uniprot/Q86Y07

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006296

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006287

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