VRK2 (NM_006296) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]
Overview
Purified recombinant protein of Human vaccinia related kinase 2 (VRK2), transcript variant 1, Asp301-Asp486, with N-terminal His tag, expressed in E. coli, 50ug
Synonyms
Vaccinia-related kinase-2; vaccinia related kinase 2; vaccinia virus B1R-related kinase 2
Gene ID
7444
UniProt
Q86Y07
Accession Number mRNA
NM_006296
Chromosomal Location
2p16.1
Expression System
E. coli
Tag
N-His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris, 8M Urea, pH8.0
Function
Druggable Genome, Protein Kinase, Transmembrane
Molecular Weight
21.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
VRK2
Species
Human
Protein ID
NP_006287
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7444
Uniprot URL
https://www.uniprot.org/uniprot/Q86Y07
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006296
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006287
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