PAFAH (PLA2G7) (NM_005084) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009]

Overview

Purified recombinant protein of Human phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7), transcript variant 1, esidues 22-441aa, with C-terminal DDK tag, secretory expressed in CHO cells, 50ug

Synonyms

LDL-PLA2; LP-PLA2; PAFAD; PAFAH

Gene ID

7941

UniProt

Q13093

Accession Number mRNA

NM_005084

Chromosomal Location

6p12.3

Expression System

CHO

Tag

C-DDK

Related Pathways

Ether lipid metabolism, Metabolic pathways

Field of Research

Ether lipid metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

1 x PBS, pH7.4, 10% glycerol.

Function

Druggable Genome, Secreted Protein

Molecular Weight

48.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.