PAFAH (PLA2G7) (NM_005084) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009]
Synonyms
LDL-PLA2; LP-PLA2; PAFAD; PAFAH
Gene ID
7941
UniProt
Q13093
Accession Number mRNA
NM_005084
Chromosomal Location
6p12.3
Expression System
CHO
Tag
C-DDK
Related Pathways
Ether lipid metabolism, Metabolic pathways
Field of Research
Ether lipid metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
1 x PBS, pH7.4, 10% glycerol.
Function
Druggable Genome, Secreted Protein
Molecular Weight
48.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLA2G7
Species
Human
Protein ID
NP_005075
Overview
Purified recombinant protein of Human phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7), transcript variant 1, esidues 22-441aa, with C-terminal DDK tag, secretory expressed in CHO cells, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7941
Uniprot URL
https://www.uniprot.org/uniprot/Q13093
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005084
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005075
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