DGCR8 Rabbit pAb (APR30437N)
Product Specifications
Background
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
Synonyms
DGCR8; C22orf12; DGCRK6; Gy1; pasha; microprocessor complex subunit DGCR8
Gene ID
54487
UniProt
Q8WYQ5
Cellular Locus
Nucleus, nucleolus
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 32kDa/82kDa/86kDa Observed MW: 110kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DGCR8 Rabbit pAb (APR24413N0) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=54487
Uniprot URL
https://www.uniprot.org/uniprot/Q8WYQ5
AA Sequence
Email for sequence
Available Sizes
Curated Selection
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