Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Rabbit pAb (APR30247N)
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
Synonyms
HDAC4/HDAC5/HDAC9
Gene ID
9759/10014/9734
UniProt
P56524/Q9UQL6/Q9UKV0
Dilution
WB 1:500 - 1:1000 IHC 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 57-65kDa/97-122kDa Observed MW: 125kDa/140kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-HDAC4-S246/HDAC5-S259/HDAC9-S220 Rabbit pAb (APR30247N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9759/10014/9734
Uniprot URL
https://www.uniprot.org/uniprot/P56524/Q9UQL6/Q9UKV0
AA Sequence
Email for sequence
Available Sizes
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