SH3PXD2A Rabbit pAb (APR30147N)
Product Specifications
Background
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs, NADPH oxidases (NOXs and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SH3PXD2A Rabbit pAb (APR30147N) .
Synonyms
SH3PXD2A; FISH; SH3MD1; TKS5
Gene ID
9644
UniProt
Q5TCZ1
Cellular Locus
Cell projection, Cytoplasm, podosome
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 102kDa/121kDa/125kDa Observed MW: 100kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9644
Uniprot URL
https://www.uniprot.org/uniprot/Q5TCZ1
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
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