Phospho-α-Synuclein-Y136 Rabbit pAb (APR29978N)
Product Specifications
Background
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Synonyms
PD1; NACP; PARK1; PARK4; SNCA
Gene ID
6622
UniProt
P37840
Cellular Locus
Cell junction, Cytoplasm, Membrane, Nucleus, Secreted, cytosol, synapse
Dilution
WB 1:500 - 1:2000 IF 1:100 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 11kDa/13kDa/14kDa Observed MW: 18KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-α-Synuclein-Y136 Rabbit pAb (APR29978N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6622
Uniprot URL
https://www.uniprot.org/uniprot/P37840
AA Sequence
Email for sequence
Available Sizes
Curated Selection
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