Phospho-CD117/c-Kit-Y719 Rabbit pAb (APR29846N)
Product Specifications
Background
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
KIT; C-Kit; CD117; PBT; SCFR; c-kit
Gene ID
3815
UniProt
P10721
Cellular Locus
Cell membrane, Cytoplasm, Single-pass type I membrane protein
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 46kDa/109kDa Observed MW: 120KDa/145KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-CD117/c-Kit-Y719 Rabbit pAb (APR29846N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3815
Uniprot URL
https://www.uniprot.org/uniprot/P10721
AA Sequence
Email for sequence
Available Sizes
Curated Selection
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