What is the catalog number for PDE12 Rabbit pAb (APR29703N)?

The catalog number for PDE12 Rabbit pAb (APR29703N) is APR29703N.

What sizes are available for PDE12 Rabbit pAb (APR29703N)?

PDE12 Rabbit pAb (APR29703N) is available in the following size(s): 50 µL, 100 µL, 200 µL.

How many pack sizes does PDE12 Rabbit pAb (APR29703N) come in?

PDE12 Rabbit pAb (APR29703N) is available in 3 different pack sizes.

Is PDE12 Rabbit pAb (APR29703N) in stock?

PDE12 Rabbit pAb (APR29703N) is currently made to order / not held in immediate stock. Contact us for lead time.

PDE12 Rabbit pAb (APR29703N)

Product Specifications

Background

Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs. Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDE12 Rabbit pAb (APR23598N0) .

Synonyms

PDE12; 2-PDE

Gene ID

201626

UniProt

Q6L8Q7

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Observed MW: 67kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=201626

Uniprot URL

https://www.uniprot.org/uniprot/Q6L8Q7

AA Sequence

AVEKLSRAEAGSQTAAGAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRVLSRIATNALKGHAKAAAAKKSRKSRPNASGGAACSGPGPEPAVFCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPAFTELQLPRYIMAGFPVCPKLSLEFGDPASSLFRWYKEAKPGAAEPEVGVPSSLSPSSPSSSWTETDVEERVYTPSNADIGLRLKLHCTPGDGQRFGHSRELESVCVVEAGPGTCTFDHRHLYTKKVTEDALIRTVSY