RBL1 Rabbit pAb (APR29096N)
Product Specifications
Background
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
PRB1; p107; CP107
Gene ID
5933
UniProt
P28749
Dilution
WB 1:1000 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 120kDa Observed MW: 115kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RBL1 Rabbit pAb (APR29096N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5933
Uniprot URL
https://www.uniprot.org/uniprot/P28749
AA Sequence
Email for sequence
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
S01YF-0622-KX31 1 Vial
SARS-CoV-2 B.1.526 (USA/NY-WadswoRoom Temperatureh-21025952-01/2021 Isolate 1) UV-Inactivated Virus PaRoom Temperatureicles
Ask
View Details MBS1181531-01 0.02 mg (E-Coli)
Recombinant Roseiflexus sp. UPF0272 protein RoseRS_0590 (RoseRS_0590)
Ask
View Details 
MBS1181531-02 0.02 mg (Yeast)
Recombinant Roseiflexus sp. UPF0272 protein RoseRS_0590 (RoseRS_0590)
Ask
View Details MBS1181531-03 0.1 mg (E-Coli)
Recombinant Roseiflexus sp. UPF0272 protein RoseRS_0590 (RoseRS_0590)
Ask
View Details MBS1181531-04 0.1 mg (Yeast)
Recombinant Roseiflexus sp. UPF0272 protein RoseRS_0590 (RoseRS_0590)
Ask
View Details MBS1181531-05 0.02 mg (Baculovirus)
Recombinant Roseiflexus sp. UPF0272 protein RoseRS_0590 (RoseRS_0590)
Ask
View Details