DNA topoisomerase I (TOP1) Rabbit pAb (APR27656N)
Selected Variant
APR27656N-01
Size: 50 µL
Product Specifications
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DNA topoisomerase I (TOP1) Rabbit pAb (APR27656N) .
Synonyms
TOP1; TOPI
Gene ID
7150
UniProt
P11387
Cellular Locus
Nucleus, nucleolus, nucleoplasm
Applications
WB (Homo sapiens)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 90kDa Observed MW: 108kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7150
Uniprot URL
https://www.uniprot.org/uniprot/P11387
AA Sequence
MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRASGDA
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