NBS1/NBN Rabbit pAb (APR27621N)
Product Specifications
Background
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Synonyms
NBN; AT-V1; AT-V2; ATV; NBS; NBS1; P95; nibrin
Gene ID
4683
UniProt
O60934
Cellular Locus
Chromosome, Nucleus, PML body, telomere
Applications
WB (Homo sapiens) IF (Homo sapiens)
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 84kDa Observed MW: 100kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NBS1/NBN Rabbit pAb (APR27621N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4683
Uniprot URL
https://www.uniprot.org/uniprot/O60934
AA Sequence
Email for sequence
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
EK240335 96 Well
Human TNFaIP6 (Tumor Necrosis Factor Alpha Induced Protein 6) ELISA Kit
Ask
View Details 
