What is the catalog number for GLUD1 Rabbit pAb (APR27559N)?

The catalog number for GLUD1 Rabbit pAb (APR27559N) is APR27559N.

What sizes are available for GLUD1 Rabbit pAb (APR27559N)?

GLUD1 Rabbit pAb (APR27559N) is available in the following size(s): 50 µL, 100 µL, 200 µL.

How many pack sizes does GLUD1 Rabbit pAb (APR27559N) come in?

GLUD1 Rabbit pAb (APR27559N) is available in 3 different pack sizes.

Is GLUD1 Rabbit pAb (APR27559N) in stock?

GLUD1 Rabbit pAb (APR27559N) is currently made to order / not held in immediate stock. Contact us for lead time.

GLUD1 Rabbit pAb (APR27559N)

Product Specifications

Background

This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLUD1 Rabbit pAb (APR27559N) .

Synonyms

GLUD1; GDH; GDH1; GLUD

Gene ID

2746

UniProt

P00367

Cellular Locus

Mitochondrion matrix

Applications

WB (unknow, A549, Homo sapiens, Mus musculus) IHC (Homo sapiens)

Dilution

WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 42kDa/46kDa/61kDa Observed MW: 52kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2746

Uniprot URL

https://www.uniprot.org/uniprot/P00367

AA Sequence

SEAVADREDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY