ORAI1 Rabbit pAb (APR27370N)
Product Specifications
Background
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1) .
Synonyms
CRACM1; IMD9; ORAT1; TAM2; TMEM142A; ORAI1
Gene ID
84876
UniProt
Q96D31
Cellular Locus
Cell membrane, Cytoplasmic vesicle, Multi-pass membrane protein, autophagosome
Applications
WB (Rattus norvegicus)
Dilution
WB 1:200 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 25kDa/32kDa Observed MW: 32-55KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ORAI1 Rabbit pAb (APR27370N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=84876
Uniprot URL
https://www.uniprot.org/uniprot/Q96D31
AA Sequence
LKKQPGQPRPTSKPPASGAAANVSTSGITPGQAAAIASTTIMVPFGLIFIVFAVHFYRSLVSHKTDRQFQELNELAEFARLQDQLDHRGDHPLTPGSHYA
Available Sizes
Curated Selection
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