MANF Rabbit pAb (APR27017N)
Product Specifications
Background
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MANF Rabbit pAb (APR27017N) .
Synonyms
MANF; ARMET; ARP
Gene ID
7873
UniProt
P55145
Cellular Locus
Secreted
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 20kDa Observed MW: 16KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7873
Uniprot URL
https://www.uniprot.org/uniprot/P55145
AA Sequence
SRALRPGDCEVCISYLGRFYQDLKDRDVTFSPATIENELIKFCREARGKENRLCYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASAR
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
ET2010-7 96 Well
Human TNF-alpha AssayMax™ ELISA Kit (Positive Control Included)
Sign In for Pricing
View Details 
C1035-22H-APC 200 µL
CAMK1G, CT (Calcium/Calmodulin-dependent Protein Kinase IG, CaM Kinase I gamma, CaM Kinase IG, CaM-KI gamma, CaMKI gamma, CaMKIG, CaMK-like CREB Kinase III, CLICK III, VWS1) (APC) discontinued
Sign In for Pricing
View Details 
