PDCD6 Rabbit pAb (APR26750N)
Product Specifications
Background
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.
Synonyms
PDCD6; ALG-2; ALG2; PEF1B
Gene ID
10016
UniProt
O75340
Cellular Locus
Endoplasmic reticulum membrane, Endosome, Nucleus, Nucleus membrane, Peripheral membrane protein
Applications
WB (Homo sapiens)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 7kDa/21kDa Observed MW: 16kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDCD6 Rabbit pAb (APR26750N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10016
Uniprot URL
https://www.uniprot.org/uniprot/O75340
AA Sequence
MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSIV
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1469771 Inquire
Recombinant Influenza A virus RNA-directed RNA polymerase catalytic subunit (PB1), partial
Ask
View Details 
MBS6207811-01 0.1 mL
PCAF (K(Lysine) Acetyltransferase 2B, CAF, P, P/CAF, PCAF) (MaxLight 490)
Ask
View Details MBS6207811-02 5x 0.1 mL
PCAF (K(Lysine) Acetyltransferase 2B, CAF, P, P/CAF, PCAF) (MaxLight 490)
Ask
View Details