NLRP12 Rabbit pAb (APR26739N)
Product Specifications
Background
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
Synonyms
NLRP12; CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2
Gene ID
91662
UniProt
P59046
Cellular Locus
Cytoplasm
Applications
WB (HUVEC cells, Mus musculus)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 31kDa/101kDa/107kDa/113kDa/114kDa/120kDa Observed MW: 120kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NLRP12 Rabbit pAb (APR26739N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=91662
Uniprot URL
https://www.uniprot.org/uniprot/P59046
AA Sequence
LWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6458020-01 0.2 mL
PAPSS1 (Bifunctional 3'-phosphoadenosine 5'-phosphosulfate Synthase 1, PAPS Synthase 1, PAPSS 1, Sulfurylase Kinase 1, SK 1, SK1, Sulfate Adenylyltransferase, ATP-sulfurylase, Sulfate adenylate Transferase, SAT, Adenylyl-sulfate Kinase, 3'-phosphoadenosin
Ask
View Details MBS6458020-02 5x 0.2 mL
PAPSS1 (Bifunctional 3'-phosphoadenosine 5'-phosphosulfate Synthase 1, PAPS Synthase 1, PAPSS 1, Sulfurylase Kinase 1, SK 1, SK1, Sulfate Adenylyltransferase, ATP-sulfurylase, Sulfate adenylate Transferase, SAT, Adenylyl-sulfate Kinase, 3'-phosphoadenosin
Ask
View Details