S 25585

S 25585 is a potent and selective neuropeptide Y (NPY) Y5 receptor antagonist. S 25585 reduces food intake but not through blockade of the NPY Y5 receptor[1].

Product Specifications

CAS Number

[263849-50-9]

UNSPSC

12352005

Target

Neuropeptide Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/s-25585.html

Purity

99.13

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CC=C1)NNC([C@H](CC2)CC[C@@H]2CNS(=O)(C3=C(C=C(C(F)(F)F)C=C3)[N+]([O-])=O)=O)=O

Molecular Formula

C22H23F3N4O6S

Molecular Weight

528.50

References & Citations

[1]Della-Zuana O, et al. A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of the NPY Y5 receptor. Int J Obes Relat Metab Disord. 2004 Apr;28 (4) :628-39.