S 25585
S 25585 is a potent and selective neuropeptide Y (NPY) Y5 receptor antagonist. S 25585 reduces food intake but not through blockade of the NPY Y5 receptor[1].
Product Specifications
CAS Number
[263849-50-9]
UNSPSC
12352005
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-25585.html
Purity
99.13
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=C1)NNC([C@H](CC2)CC[C@@H]2CNS(=O)(C3=C(C=C(C(F)(F)F)C=C3)[N+]([O-])=O)=O)=O
Molecular Formula
C22H23F3N4O6S
Molecular Weight
528.50
References & Citations
[1]Della-Zuana O, et al. A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of the NPY Y5 receptor. Int J Obes Relat Metab Disord. 2004 Apr;28 (4) :628-39.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPY Y5 receptor
Available Sizes
Curated Selection
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