What is the catalog number for FDPS Rabbit pAb (APR26065N)?

The catalog number for FDPS Rabbit pAb (APR26065N) is APR26065N.

What sizes are available for FDPS Rabbit pAb (APR26065N)?

FDPS Rabbit pAb (APR26065N) is available in the following size(s): 50 µL, 100 µL, 200 µL.

How many pack sizes does FDPS Rabbit pAb (APR26065N) come in?

FDPS Rabbit pAb (APR26065N) is available in 3 different pack sizes.

Is FDPS Rabbit pAb (APR26065N) in stock?

FDPS Rabbit pAb (APR26065N) is currently made to order / not held in immediate stock. Contact us for lead time.

FDPS Rabbit pAb (APR26065N)

Product Specifications

Background

This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FDPS Rabbit pAb (APR26065N) .

Synonyms

FDPS; FPPS; FPS; POROK9

Gene ID

2224

UniProt

P14324

Cellular Locus

Cytoplasm

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 40kDa/48kDa Observed MW: 38kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2224

Uniprot URL

https://www.uniprot.org/uniprot/P14324

AA Sequence

IGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK