RANTES Rabbit pAb (APR25961N)
Product Specifications
Background
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Synonyms
CCL5; D17S136E; RANTES; SCYA5; SIS-delta; SISd; TCP228; eoCP
Gene ID
6352
UniProt
P13501
Cellular Locus
Secreted
Applications
WB (Mus musculus) IHC (Mus musculus)
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 9kDa Observed MW: 13kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RANTES Rabbit pAb (APR25961N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6352
Uniprot URL
https://www.uniprot.org/uniprot/P13501
AA Sequence
SPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2578374 5x 96 Tests
Uncoated Porcine LDLR (Low Density Lipoprotein Receptor) ELISA Kit
Ask
View Details 
abx495906-01 96 Tests
Human Coiled Coil And C2 Domain Containing 1A (CC2D1A) CLIA Kit
Ask
View Details 
abx495906-02 5x 96 Tests
Human Coiled Coil And C2 Domain Containing 1A (CC2D1A) CLIA Kit
Ask
View Details abx495906-03 10x 96 Tests
Human Coiled Coil And C2 Domain Containing 1A (CC2D1A) CLIA Kit
Ask
View Details