VEGFR1 Rabbit pAb (APR25942N)
Product Specifications
Background
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Synonyms
FLT; FLT-1; VEGFR-1; VEGFR1; FLT1
Gene ID
2321
UniProt
P17948
Cellular Locus
Cell membrane, Cytoplasm, Endosome, Secreted, Single-pass type I membrane protein
Applications
WB (unknow)
Dilution
WB 1:500 - 1:1000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 39kDa/41kDa/52- 82kDa/150kDa Observed MW: 180kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VEGFR1 Rabbit pAb (APR25942N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2321
Uniprot URL
https://www.uniprot.org/uniprot/P17948
AA Sequence
Email for sequence
Available Sizes
Curated Selection
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