RIPK3 Rabbit pAb (APR25825N)
Product Specifications
Background
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RIPK3 Rabbit pAb (APR25825N) .
Synonyms
RIPK3; RIP3
Gene ID
11035
UniProt
Q9Y572
Cellular Locus
Cell membrane, Cytoplasm, Mitochondrion, cytosol
Applications
WB (human kidney cancer cells, Ctenopharyngodon idellus, Gallus gallus, Mus musculus, Homo sapiens, Rattus norvegicus) IHC (Gallus gallus, Mus musculus)
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 25kDa/27kDa/56kDa Observed MW: 57KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=11035
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y572
AA Sequence
MSCVKLWPSGAPAPLVSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRL
Available Sizes
Frequently Asked Questions
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