PHD2 Rabbit pAb (APR24751N)
Product Specifications
Background
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3) .
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PHD2 Rabbit pAb (APR24751N) .
Synonyms
EGLN1; C1orf12; ECYT3; HALAH; HIF-PH2; HIFPH2; HPH-2; HPH2; PHD2; SM20; ZMYND6
Gene ID
54583
UniProt
Q9GZT9
Cellular Locus
Cytoplasm, Nucleus
Dilution
IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 36kDa/43kDa/46kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=54583
Uniprot URL
https://www.uniprot.org/uniprot/Q9GZT9
AA Sequence
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDSVGKDVF
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
041442-Biotin 200 µL
SC31B, CT (SEC31B, SEC31L2, Protein transport protein Sec31B, SEC31-like protein 2, SEC31-related protein B, SEC31B-1) (Biotin) discontinued
Sign In for Pricing
View Details 029155 100 µg
FK506 Binding Protein 1A (FKBP1A, FKBP-1A, FKBP1, FK506 Binding Protein 12kD, FKBP12, FKBP12C, Immunophilin FKBP-12, Peptidyl-prolyl Cis-trans Isomerase FKBP1A, PPIase, PKC12, PKCI2, Rotamase) (Biotin)
Sign In for Pricing
View Details NBP2-68486R 0.5 mL
Goat Polyclonal Goat anti-Rat IgG2a Secondary Antibody [DyLight 550]
Sign In for Pricing
View Details C1035-22E2-AP 200 µL
CAMK1D, NT (Calcium/Calmodulin-dependent Protein Kinase Type 1D, CaM kinase ID, CaM Kinase I delta, CaMKI-delta, CaM-KI delta, CaMKI delta, Camk1D, CamKI-like Protein Kinase, CKLiK, CamKI-like Protein Kinase) (AP) discontinued
Sign In for Pricing
View Details