CDKN2C/p18-INK4C Rabbit pAb (APR24569N)
Product Specifications
Background
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
Synonyms
CDKN2C; INK4C; p18; p18-INK4C
Gene ID
1031
UniProt
P42773
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 18kDa Observed MW: 18kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDKN2C/p18-INK4C Rabbit pAb (APR24569N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1031
Uniprot URL
https://www.uniprot.org/uniprot/P42773
AA Sequence
MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
15711124 3 x 1.0μg DNA
CDK5RAP2 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details 
MBS951531-01 0.02 mg (E-Coli)
Recombinant Human Ornithine decarboxylase antizyme 1 (OAZ1)
Ask
View Details MBS951531-02 0.1 mg (E-Coli)
Recombinant Human Ornithine decarboxylase antizyme 1 (OAZ1)
Ask
View Details