TGF beta Receptor I (TGFBR1) Rabbit pAb (APR23459N)
Product Specifications
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TGF beta Receptor I (TGFBR1) Rabbit pAb (APR23459N) .
Synonyms
TGFBR1; AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; TGFR-1; tbetaR-I; TBRI; TBR-i
Gene ID
7046
UniProt
P36897
Cellular Locus
Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction
Applications
WB (Homo sapiens, Rattus norvegicus, Mus musculus)
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 56kDa Observed MW: 56KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7046
Uniprot URL
https://www.uniprot.org/uniprot/P36897
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
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