IL1β Rabbit pAb (APR22874N)
Product Specifications
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL1β Rabbit pAb (APR22867N8) .
Synonyms
IL-1; IL1-BETA; IL1F2; IL1 beta; IL1B
Gene ID
3553
UniProt
P01584
Cellular Locus
Cytoplasm, Cytoplasmic vesicle, Lysosome, Secreted, autophagosome, cytosol, exosome
Applications
WB (Homo sapiens, Rattus norvegicus, Mus musculus, Danio rerio, Gallus gallus) IHC (Rattus norvegicus, Homo sapiens) IF (Mus musculus, Homo sapiens)
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 30kDa Observed MW: 31KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3553
Uniprot URL
https://www.uniprot.org/uniprot/P01584
AA Sequence
Email for sequence
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSH030897 50 µg
Recombinant Human STK23/MSSK1/SRPK3 Protein (His & GST Tag)
Sign In for Pricing
View Details ![Cyclin A2 Recombinant Rabbit Monoclonal Antibody [SD2052]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea81444/imageurl/et1612-26.webp)
ET1612-26 100 µL
Cyclin A2 Recombinant Rabbit Monoclonal Antibody [SD2052]
Sign In for Pricing
View Details 
![Elab Fluor® 488 Anti-Human CD5 Antibody[5D7]](https://cdn.genprice.uk/products/763/68dd14b0061270361e7d3b08/imageurl/e-ab-f1371l.webp)
E-AB-F1371L-01 20 Tests
Elab Fluor® 488 Anti-Human CD5 Antibody[5D7]
Sign In for Pricing
View Details