Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Caveolin-1 Rabbit pAb (APR22117N)

Product Specifications

Background

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Caveolin-1 Rabbit pAb (APR22117N) .

Synonyms

BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21; CAV1

Gene ID

857

UniProt

Q03135

Cellular Locus

Cell membrane, Golgi apparatus membrane, Membrane, Membrane raft, Peripheral membrane protein, caveola

Applications

WB (Mus musculus, Homo sapiens) IF (Mus musculus) IHC (Homo sapiens)

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 17kDa/20kDa Observed MW: 20kDa/23kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=857

Uniprot URL

https://www.uniprot.org/uniprot/Q03135

AA Sequence

MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFY

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human DIO1 activation kit by CRISPRa
GA101202 1 Kit

Human DIO1 activation kit by CRISPRa

Sign In for Pricing
View Details
5-Amino-2,4-di-tert-butylphenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
TRC-A554230-250MG 250 mg

5-Amino-2,4-di-tert-butylphenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

Sign In for Pricing
View Details
Zdhhc14 Mouse Gene Knockout Kit (CRISPR)
KN519678 1 Kit

Zdhhc14 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
EFHD1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI8F3]
TA812755AM 100 µL

EFHD1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI8F3]

Sign In for Pricing
View Details
Human LGR7 (RXFP1) activation kit by CRISPRa
GA111834 1 Kit

Human LGR7 (RXFP1) activation kit by CRISPRa

Sign In for Pricing
View Details
VPS26B (NM_052875) Human Recombinant Protein
TP310499L 1 mg

VPS26B (NM_052875) Human Recombinant Protein

Sign In for Pricing
View Details