URM1 Rabbit pAb (APR20382N)
Product Specifications
Background
Acts as a sulfur carrier required for 2-thiolation of mcm (5S (2U at tRNA wobble positions of cytosolic tRNA (Lys, tRNA (Glu and tRNA (Gln. Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm (5S (2U. Also acts as a ubiquitin-like protein (UBL that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Synonyms
URM1; C9orf74
Gene ID
81605
UniProt
Q9BTM9
Cellular Locus
Cytoplasm
Dilution
WB 1:500 - 1:2000 IF 1:50 - 1:100
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 7kDa/11kDa/15kDa Observed MW: 11kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality URM1 Rabbit pAb (APR20382N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=81605
Uniprot URL
https://www.uniprot.org/uniprot/Q9BTM9
AA Sequence
MAAPLSVEVEFGGGAELLFDGIKKHRVTLPGQEEPWDIRNLLIWIKKNLLKERPELFIQGDSV
Available Sizes
Curated Selection
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