C-Myc Rabbit pAb (APR19686N)

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality c-Myc Rabbit pAb (APR19686N) .

WB (unknow, Human Bladder Cancer, Mus musculus, Homo sapiens, Gallus gallus, Sus scrofa) ChIP (Homo sapiens, Mus musculus) Co-IP (Homo sapiens, Mus musculus, Homo sapiens, Gallus gallus) IP (Homo sapiens, Mus musculus)