What is the catalog number for TDG Rabbit pAb (APR19249N)?

The catalog number for TDG Rabbit pAb (APR19249N) is APR19249N.

What sizes are available for TDG Rabbit pAb (APR19249N)?

TDG Rabbit pAb (APR19249N) is available in the following size(s): 50 µL, 100 µL, 200 µL.

How many pack sizes does TDG Rabbit pAb (APR19249N) come in?

TDG Rabbit pAb (APR19249N) is available in 3 different pack sizes.

Is TDG Rabbit pAb (APR19249N) in stock?

TDG Rabbit pAb (APR19249N) is currently made to order / not held in immediate stock. Contact us for lead time.

TDG Rabbit pAb (APR19249N)

Product Specifications

Background

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TDG Rabbit pAb (APR19249N) .

Synonyms

TDG; hTDG

Gene ID

6996

UniProt

Q13569

Cellular Locus

Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 46kDa Observed MW: 60kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6996

Uniprot URL

https://www.uniprot.org/uniprot/Q13569

AA Sequence

MEAENAGSYSLQQAQAFYTFPFQQLMAEAPNMAVVNEQQMPEEVPAPAPAQEPVQEAPKGRKRKPRTTEPKQPVEPKKPVESKKSGKSAKSKEKQEKITDTFKVKRKVDRFNGVSEAELLTKTLPDILTFNLDIVIIGINPGLMAAYKGHHYPGPGNHFW