CP26

CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress[1].

Product Specifications

CAS Number

[500285-30-3]

UNSPSC

12352005

Target

E1/E2/E3 Enzyme

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cp26.html

Purity

98.19

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

ClC(C(Cl)=C/1Cl)=C(Cl)C1=C\C2=CC=C(C)C=C2

Molecular Formula

C13H8Cl4

Molecular Weight

306.01

References & Citations

[1]Jingjing Ruan, et al. A small molecule inhibitor of ER-to-cytosol protein dislocation exhibits anti-dengue and anti-Zika virus activity. Sci Rep. 2019 Jul 29;9 (1) :10901.