MYBPC3 Rabbit pAb (APR18981N)
Product Specifications
Background
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Synonyms
MYBPC3; CMD1MM; CMH4; FHC; LVNC10; MYBP-C; cardiac
Gene ID
4607
UniProt
Q14896
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 140kDa Observed MW: 170kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYBPC3 Rabbit pAb (APR18981N) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4607
Uniprot URL
https://www.uniprot.org/uniprot/Q14896
AA Sequence
SSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1494995-01 0.05 mg
Rabbit anti-human Uncharacterized protein C9orf163 polyclonal Antibody(C9orf163), FITC
Ask
View Details MBS1494995-02 0.1 mg
Rabbit anti-human Uncharacterized protein C9orf163 polyclonal Antibody(C9orf163), FITC
Ask
View Details 
MBS1494995-03 5x 0.1 mg
Rabbit anti-human Uncharacterized protein C9orf163 polyclonal Antibody(C9orf163), FITC
Ask
View Details 