MICU2 Rabbit pAb (APR18870N)
Product Specifications
Background
Key regulator of mitochondrial calcium uniporter (MCU required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.
Synonyms
MICU2; 1110008L20Rik; EFHA1
Gene ID
221154
UniProt
Q8IYU8
Cellular Locus
Mitochondrion intermembrane space
Applications
WB (Rattus norvegicus, Homo sapiens) IP (Homo sapiens)
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 49kDa Observed MW: 45KDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MICU2 Rabbit pAb (APR18863N8) .
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=221154
Uniprot URL
https://www.uniprot.org/uniprot/Q8IYU8
AA Sequence
AWHHSRVSVAARDGSFTVSAQKNVEHGIIYIGKPSLRKQRFMQFSSLEHEGEYYMTPRDFLFSVMFEQMERKTSVKKLTKKDIEDTLSGIQTAGCGSTFFR
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6479169-01 0.2 mL
GDF3, NT (Growth/Differentiation Factor 3, GDF-3, UNQ222/PRO248) (AP)
Ask
View Details MBS6479169-02 5x 0.2 mL
GDF3, NT (Growth/Differentiation Factor 3, GDF-3, UNQ222/PRO248) (AP)
Ask
View Details 
11826124 3 x 1.0μg DNA
AMD1 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details 
MBS7030918-01 0.02 mg
Recombinant Papio hamadryas Taste receptor type 2 member 13 (TAS2R13)
Ask
View Details