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Α-Smooth Muscle Actin (ACTA2) Rabbit pAb (APR17738N)

Product Specifications

Background

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Synonyms

AAT6; ACTSA; MYMY5; ACTA2; actin

Gene ID

59

UniProt

P62736

Cellular Locus

Cytoplasm, cytoskeleton

Applications

WB (Mus musculus, Rattus norvegicus, Homo sapiens) IF (Mus musculus, Rattus norvegicus) IHC (Mus musculus, Rattus norvegicus)

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:100 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 42kDa Observed MW: 42KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality α-Smooth Muscle Actin (ACTA2) Rabbit pAb (APR17738N) .

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=59

Uniprot URL

https://www.uniprot.org/uniprot/P62736

AA Sequence

MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQI

Available Sizes

Curated Selection

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